1629 - The first traders from the English settlements began trading among the Cherokees.
1721 - The Cherokee Treaty with the Governor of the Carolinas is thought to be the first consession of land.
1785 - Treaty of Hopewell is the first treaty between the U.S. and the Cherokees.
1791 - Treaty of Holston signed. Includes a call for the U.S. to advance civilization of the Cherokees by giving them farm tools and technical advice.
1802 - Jefferson signs Goergia Compact.
1817 - Treaty makes exchange for land in Arkansas. Old settlers begin voluntary migration and establish a government there. In 1828, they are forced to move into Indian territory.
1821 - Sequoyah's Cherokee Syllabary completed, quickly leads to almost total literacy among the Cherokees.
1822 - Cherokee's Supreme Court established.
1824 - First written law of Western Cherokees.
1825 - New Echota, GA authorized as Cherokee capital.
1827 - Modern Cherokee Nation begins with Cherokee Constitution established by a convention; John Ross elected chief.
1828 - Cherokee Phoenix published in English and Cherokee; Andrew Jackson elected President. Gold discovered in Georgia.
1828-1830 - Georgia Legislature abolishes tribal government and expands authority over Cherokee country.
1832 - US Supreme Court decision Worcester vs Georgia establishes tribal sovereignty, protects Cherokees from Georgia laws. Jackson won't enforce decision and Georgia holds lottery for Cherokee lands.
1835 - Treaty Party signs Treaty of New Echota, giving up title to all Cherokee lands in southeast in exchange for land in Indian Territory (now Oklahoma.).
1838-1839 - Trails of Tears. US Government's forced removal of 17,000 Cherokees, in defiance of Supreme Court decision. More than 4,000 die from exposure and disease along the way.
1839 - Assassination of Treaty Party leaders, Major Ridge, John Ridge, and Elias Boudinot for breaking pact not to sign Treaty of New Echota. Factionalism continues until 1846. New constitution ratified at convention uniting Cherokees arriving from the east with those in the west.
1844 Cherokee Supreme Court building opens; Cherokee Advocate becomes the first newspaper in Indian territory.
1851 - Cherokee male and female seminaries open. Female seminary is the first secondary school for girls west of the Mississippi.
1859 - Original Keetoowah Society organized to maintain traditions and fight slavery.
1860 - Tension mounts between Union Cherokees and Confederate Cherokees. Civil War begins.
1861 - Treaty signed at Park Hill between Cherokee Nation and the Confederate government. Cherokee Nation torn by border warfare throughout the Civil War.
1865-1866 - Cherokee must negotiate peace with the US Government. New treaty limits tribal land rights, eliminates possibility of Cherokee State and is prelude to Dawes Commission. John Ross dies.
1887 - General Allotment Act passed; requires individual ownership of lands once held in common by Indian tribes.
1889 - Unassigned lands in Indian Territory opened by white settlers known as "boomers."
1890 - Oklahoma Territory organized out of western half of Indian Territory.
1893 - Cherokee Outlet opened for white settlers.Dawes Commission arrives.
1898 - Curtis Act passed abolishing tribal courts.
1903 - W.C. Rogers becomes last elected chief for 69 years.
1905 - Land allotment begins after official roll taken of Cherokees.
1907 - Oklahoma statehood combines Indian and Oklahoma Territories and dissolves tribal government.
1917 - William C. Rogers, the last Cherokee Chief, dies.
1934 - Indian Reorganization Act established a landbase for tribes and legal structure for self government.
1948 - Chief J.B.Milam calls Cherokee Convention; beginning of model tribal government of the Cherokee Nation.
1949 - W.W. Bill Keeler appointed chief by President Harry Truman.
1957 - First Cherokee National Holiday.
1961 - Cherokees awarded 15 million dollars by the US Claims Commission for Cherokee Outlet Lands.
1963 - Cherokee National Historical Society founded. CNHS opens Ancient Village, 1967; Trail of Tears Drama, 1969, and museum, 1975.
1967 - Cherokee Foundation formed to purchase land on which the tribal complex now sits.
1970 - U.S. Supreme Court ruling confirms Cherokee Nation ownership of bed and banks of 96 mile segment of Arkansas Riverbed.
1971 - W.W.Keeler becomes first elected principal chief since statehood.
1975 - Ross O. Swimmer elected to first of three terms as principal chief. First Cherokee Tribal Council elected Congress passes Indian Self-Determination and Education Assistance Act.
1976 - Cherokee voters ratify new Constitution outlining tribal government.
1979 - Tribal offices moved into modern new complex South of Tahlequah.
1984 - First joint council meeting in 146 years between Eastern Band of Cherokees and Cherokee Nation held at Red Clay, TN. Council meetings now held bi-annually.
1987 - Wilma Mankiller makes history and draws international attention to tribe as first woman elected chief; Cherokee voters pass constitution amendment to elect council by districts in 1991.
1988 - Cherokee Nation joins Eastern Band in Cherokee, NC to commemorate beginning of The Trail of Tears.
1989 - The Cherokee Nation observes 150th anniversary of arrival in Indian Territory. "A New Beginning".
1990 - Chief Mankiller signs the historic self-governance agreement, making the Cherokee Nation one of six tribes to participate in the self-determination project. The project, which ran for three years beginning Oct.1 1990, authorized the tribe to assume tribal responsiblity for BIA funds which were formerly being spent on the tribe's behalf at the agency, area and central office levels.
1991 - In the July tribal election the first council to be elected by districts since statehood and Wilma Mankiller won second elected term as principal chief with a landslide 82% of the votes cast.
1995 - Joe Byrd and Garland Eagle elected principal chief and deputy chief which marks the first time in nearly 200 years that full blood bilingual leaders occupy the top positions of the Cherokee Nation.